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Labor Secretary Chavez-DeRemer resigns, third Cabinet exit in Trump’s second term

By Estefano Gomez · Published April 20, 2026 · 2 min read · Source: Crypto Briefing
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Labor Secretary Lori Chavez-DeRemer has resigned to take a private-sector role, making her the third Cabinet departure in Trump’s second term. The “Next to Leave Trump Cabinet” market on Polymarket is directly affected.

Market reaction

Chavez-DeRemer’s departure answers the core question of whether anyone would leave the Trump Cabinet before 2027. The Next to Leave Trump Cabinet market should shift accordingly. With 255 days left in the year, odds will adjust around the possibility of further departures given ongoing internal frictions.

The “Trump out as President by April 30” market is unaffected. Odds for Trump no longer being President by end of April sit at 0.7% YES, down from 1% a week ago. A Cabinet member leaving has no bearing on Trump’s presidency status.

Why it matters

The resignation follows investigations into alleged misconduct, including claims of an affair, misuse of taxpayer funds, and civil rights complaints. Deputy Secretary Keith Sonderling will serve as acting Labor Secretary. The Next to Leave Trump Cabinet market now prices in greater uncertainty around other Cabinet members facing scrutiny or potential exits.

At 22¢, a YES share in the “Next to Leave Trump Cabinet” market pays $1, representing a potential return for traders who expect further resignations. New allegations or confirmed internal disputes could move odds further.

What to watch

Statements from White House Communications Director Steven Cheung or new Cabinet changes announced on Trump’s social media platforms would provide the clearest signals of additional shifts within the administration.

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